Police believe the driver, a 29-year-old Fort Wayne man had been speeding prior to the crash late Sunday evening.
Conservation officers have not said if the man was issued any citations.
Among the badly injured are a 4-year-old and 12-year-old boy.
Investigators said the driver failed to make a turn on Business 24 and crashed into a yard Saturday evening.
A tractor-trailer slammed into the back of a car and then hit a flatbed truck hauling steel bars on I-70 in western Indiana on Saturday.
Police say an SUV driver was trying to pass another vehicle in a no-passing zone when he crossed a double yellow line dividing the roadway and hit another vehicle head-on
Police say the 18-year-old from Illinois ignored a stop sign and her car collided with a semi just before 6:30 a.m.
A Fort Wayne Community Schools bus crashed into a home at Broadway and Home Avenue and was lodged in the structure.
Witnesses told police the motorcycle driver was traveling approximately 70 to 110 miles per hour.
Two people were hospitalized with non-life threatening injuries.
The crash was reported at the 303 milemarker of Interstate 69, one mile north of the Jefferson Boulevard/U.S. 24 interchange.
A semi and a Pontiac Grand Prix collided in the intersection of U.S. 33 and U.S. 127 just north of Celina, Ohio. It’s not clear who had the right of way.
The incident took place just before 11 p.m. Monday in DeKalb County after the driver of a pickup truck had gotten out of his vehicle to tell a police officer stopped on the shoulder of I-69 about a possible drunk driver.
An autopsy conducted by the Allen County Coroner’s office determined the 49-year-old Fort Wayne man took his own life when he was struck by a semi early Friday afternoon.
A Ford Taurus drifted left of center, side-swiped an SUV then hit a Mercedes head-on. The driver suffered head injuries.
Two people on the motorcycle were sent to the hospital with life-threatening injuries.
Police learned the 17-year-old driver was speeding and late for an appointment when lost control, causing her car to roll end over end near Terre Haute Monday evening.
Police said a southbound Toyota turned left in front of a 2005 Chevy Cavalier without yielding. The impact sent the Toyota onto its side, trapping the drive and two young children.
Indiana Conservation officers are investigating the crash that took place late Saturday afternoon in Noble County.
The crash took place just before 3:20 a.m. on a county road in DeKalb County when the driver lost control and drove into a ditch.